Phase ii study of cisplatin and oral vp16 in patients with refractory or relapsed ewing sarcoma. Cisplatin combined with oral vp16 is well tolerated and has acceptable side effects but limited clinical activity in refractory relapsed esft. Abdominal or stomach pain severe blistering peeling or loosening of the skin cough or hoarseness dark urine diarrhea difficult breathing drowsiness joint or muscle pain loss of appetite lower back or side pain muscle tremors nausea or vomiting rapid deep breathing red irritated eyes red skin.
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